Download Anatomy of a Scientific Discovery: The Race to Find the by Jeff Goldberg PDF

By Jeff Goldberg

In overdue 1973, scientists John Hughes and Hans Kosterlitz spent nearly all of their time in an underfunded, vague, and cramped laboratory in Aberdeen, Sweden. whereas engaged on the brains of pigs, the duo chanced on a nonaddictive narcotic chemical that they was hoping to later locate in human brains. in the event that they may well isolate this chemical in people, probably they can give you the option to assist the realm start to heal itself. Hughes and Kosterlitz’s study could necessarily cause them to realize endorphins, the body’s personal average morphine and the chemical that makes it attainable to believe either ache and pleasure.

Announcing their findings to the medical global thrust Hughes and Kosterlitz within the highlight and made them celebrities. quickly, scientists worldwide have been rapidly interpreting the human mind and its endorphins. In many years’ time, they'd use the team’s preliminary study to hyperlink endorphins to drug dependancy, runner’s excessive, urge for food keep watch over, sexual reaction, and psychological health problems akin to melancholy and schizophrenia.

In Anatomy of a systematic Discovery, Jeff Goldberg describes Hughes and Kosterlitz’s lives earlier than, in the course of, and after their historical and medical leap forward. He additionally takes a glance on the higher photo, revealing the brutal pageant among drug businesses to discover the way to benefit from this enormous discovery.

Show description

Read or Download Anatomy of a Scientific Discovery: The Race to Find the Body's Own Morphine PDF

Best methodology & statistics books

Handbook of Media for Environmental Microbiology

Atlas (biology and public overall healthiness, U. of Louisville) provides a few 2000 alphabetical entries that supply info on media which are used for environmental microbial analyses, protecting the diversity of media had to domesticate the variety of microorganisms which are culurable. each one access offers the names and synonyms of media, description of composition, directions for guidance, advertisement assets, makes use of, and safeguard cautions the place wanted.

Implementing Reproducible Research

In computational technological know-how, reproducibility calls for that researchers make code and information to be had to others in order that the knowledge should be analyzed in the same demeanour as within the unique e-book. Code has to be on hand to be allotted, information needs to be obtainable in a readable layout, and a platform needs to be to be had for greatly dispensing the information and code.

Bogus Science: Some People Really Believe These Things

We delight ourselves at the medical tradition during which we are living, yet is it relatively so clinical? Is it now not the fact that huge elements of our society are awash with rules and preconceptions that can no longer be additional divorced from technology, although usually they're wrongly or fraudulently defined as "scientific"?

Additional info for Anatomy of a Scientific Discovery: The Race to Find the Body's Own Morphine

Example text

The butcher lined up fresh heads, which Hughes would toss aside when he finished with them. By the end of the morning a pile of twenty or so would accumulate at his feet. The sky lightened gradually. The sun, an unwarming, pale disk, rose at about eight, and all work came to a halt shortly after ten. Hughes collected his equipment and washed his hands at a cold water faucet. As the men began to leave for the Butcher’s Arms or some other nearby pub, rats came out to scavenge the bloody refuse in the slaughterhouse’s open field.

Despite the rather insalubrious atmosphere of the “frog” room—Kosterlitz’s dank, dingy lab in the Marishal College basement, where the frogs had once been stored for student dissections—David Wallis, a senior research fellow at the time, recalls that work was proceeding in a good-natured fashion in 1963, when Kosterlitz first began to talk about the possibility that the body might contain its own opiates, which worked to slow down the digestive spasms in living animals, the same way morphine did on the ileum.

Despite the rather insalubrious atmosphere of the “frog” room—Kosterlitz’s dank, dingy lab in the Marishal College basement, where the frogs had once been stored for student dissections—David Wallis, a senior research fellow at the time, recalls that work was proceeding in a good-natured fashion in 1963, when Kosterlitz first began to talk about the possibility that the body might contain its own opiates, which worked to slow down the digestive spasms in living animals, the same way morphine did on the ileum.

Download PDF sample

Rated 4.99 of 5 – based on 14 votes