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Download Allergic skin disease: a multidisciplinary approach by Donald Y.M. Leung, Malcolm W. Greaves PDF

By Donald Y.M. Leung, Malcolm W. Greaves

This state-of-the-science reference offers worthy info at the pathophysiology and monetary and social outcomes of allergic pores and skin reactions, in addition to new remedies in accordance with rising ideas of pores and skin sickness pathobiology-addressing the epidemiology, mechanisms, occupational results, environmental triggers, and quality-of-life matters. makes a speciality of atopic dermatitis, urticaria, and allergic touch dermatitis, between different more and more universal pores and skin problems. Written via greater than 35 prime researchers, Allergic pores and skin ailment ·reviews easy ideas of the motives of allergic epidermis responses ·analyzes the position of key phone varieties, effector molecules, cytokines, mediators, chemokines, telephone adhesion molecules, and immunogenetic mechanisms ·showcases the dynamics of adhesion molecules and the pathophysiology of pruritus ·examines medical beneficial properties of epidermis bronchial asthma, rather relating to immune mechanisms that be sure pathogenic path and end result ·investigates behaviors of keratinocytes, dendritic cells and macrophages, fibroblasts, lymphocytes, granulocytes, and endothelial cells ·explores phototherapy, photochemotherapy, immunomodulatory remedy, and conventional antiinflammatory treatment for recalcitrant pores and skin illnesses ·discusses anaphylaxis and different allergies to insect bites ·surveys demographism, vibratory angioedema, and different varieties of urticaria ·identifies allergic and infectious triggers of dermis affliction ·and extra! Containing over 1800 bibliographic citations, Allergic pores and skin affliction is a must-read source for dermatologists, allergists, immunologists, pharmaceutical and beauty chemists, internists, pediatricians, and graduate and clinical tuition scholars in those disciplines.

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Donald Y. M. Leung Malcolm W. Greaves Page v Contents Preface iii Contributors vii PART ONE: GENERAL PRINCIPLES 1. Epidemiology and Socioeconomic Impact of Allergic Skin Diseases Finn Schultz Larsen 1 2. Economic Evaluations in Allergic Skin Diseases Rukmini Rajagopalan 21 3. Molecular Mechanisms of Allergic Skin Responses Robert C. Fuhlbrigge and Thomas S. Kupper 29 4. Cellular Mechanisms of Allergic Skin Responses Kefei Kang, Seth R. Stevens, and Kevin D. Cooper 53 5. Adhesion Molecules and Their Role in Allergic Skin Diseases Bruce S.

Year of age Instrument Lifetime prevalence (%) Comments Stuckey [130] adults Q 7 Western Australia Herbert [131] male adults Q 4* Canada Wiithrich [132] 10–74 Q 5 Switzerland Golden [133] adults Q 22** Industrial workers, US Charpin [134] adults Q 11* South France * = 1% systemic allergic reaction; ** = 3% systemic allergic reaction. ] Age Lifetime prevalence (%) Positive RAST (%) Comments Stuckey [130] adults 7 16 Western Australia Herbert [131] male adults 4 12 Canada Golden [133] adults 22 17* Industrial workers, US Müller [134] adults 12 18 Blood donors, Switzerland * = 23% positive venom skin prick test.

90. Åberg N, Engström I, Lindberg U. Allergic diseases in Swedish school children. Acta Pædiatr Scand 1989; 78:246–252. 91. Bakke P, Gulsvik A, Eide GE. Hay fever, eczema and urticaria in southwest Norway. Allergy 1990; 45:515–522. 92. Keiding L. Asthma, Allergy and Other Types of Hypersensitivity in Denmark—and the Development 1987–1994. Copenhagen: Danish Institute for Clinical Epidemiology (DICE), 1997. 93. Ebken RK, Bauschard FA, Levine MI. Dermographism: its definition, demonstration and prevalence.

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